Igumbi Lokuhlanza: Ayinyumba ngokwedlulele, ngisho nechashaza lothuli lingabhubhisa ama-chips abiza izigidi; Imvelo: Nakuba ingase ibonakale ingcolile futhi ingcolile, igcwele ubungqabavu. Umhlabathi, ama-microorganisms, nempova empeleni kwenza abantu babe nempilo enhle.
Kungani lezi ezimbili 'ezihlanzekile' zihlala ndawonye? Zibulolonge kanjani ubuchwepheshe nempilo yabantu? Lesi sihloko sihlaziya kusuka ezinhlangothini ezintathu: ukuziphendukela kwemvelo, i-immunology, nokuthuthukiswa kwezwe.
1. Ukuphikisana kokuziphendukela kwemvelo: Umzimba womuntu uvumelana nemvelo, kodwa impucuko idinga indawo ehlanzekile kakhulu.
(1). Inkumbulo yofuzo lomuntu: "Ukungcola" kwemvelo kuyinto evamile. Izigidi zeminyaka, okhokho babantu babehlala endaweni egcwele ama-microorganisms, ama-parasites, nama-antigens emvelo, futhi amasosha omzimba agcina ibhalansi ngokusebenzisa "izimpi" eziqhubekayo. Isisekelo sesayensi: I-Hygiene Hypothesis iphakamisa ukuthi ukuchayeka kwasebuntwaneni enanini elilinganiselwe lama-microorganisms (njengama-probiotics enhlabathini nasesikhumbeni sezilwane) kungaqeqesha amasosha omzimba futhi kunciphise ingozi yokungezwani komzimba nezifo ezizimele.
(2). Isidingo sezimboni zanamuhla: Indawo ehlanzekile kakhulu iyitshe legumbi lobuchwepheshe. Ukukhiqizwa kwe-chip: izinhlayiya zothuli eziyi-micron engu-0.1 zingabangela ukujikeleza okufushane kwe-chip engu-7nm, futhi ukuhlanzeka komoya endaweni yokusebenzela ehlanzekile kudinga ukufinyelela ku-ISO 1 (≤ izinhlayiya eziyi-12 nge-cubic meter ngayinye). Ukukhiqizwa kwemithi: Uma imigomo nemijovo kungcoliswe amagciwane, kungase kubangele imiphumela ebulalayo. Amazinga e-GMP adinga ukuthi ukugxila kwama-microbial ezindaweni ezibucayi kusondele ku-zero.
Esikudingayo ekuqhathaniseni amacala akukhona ukukhetha phakathi kokubili, kodwa ukuvumela izinhlobo ezimbili "zokuhlanzeka" ukuthi zihlalisane: ukusebenzisa ubuchwepheshe ukuvikela ukukhiqizwa okunembayo nokusebenzisa imvelo ukondla amasosha omzimba.
2. Ibhalansi ye-immunological: indawo ehlanzekile nokuchayeka kwemvelo
(1). Isakhiwo somugqa, ithoni yombala owodwa, nezinga lokushisa elingashintshi kanye nokuswakama kwegumbi lokuhlanza ngokugqamayo kusebenza kahle, kodwa kwephula ukuhlukahluka kwezinzwa okuguqulelwe ekuziphendukeleni kwemvelo komuntu futhi kungaholela kalula "kusifo segumbi eliyinyumba" (ubuhlungu bekhanda/ukucasuka).
(2). Isimiso siwukuthi i-Mycobacterium vaccae enhlabathini ingashukumisa ukukhishwa kwe-serotonin, okufana nomphumela wezidakamizwa zokucindezeleka; I-Fenadine eguquguqukayo yezitshalo inganciphisa i-cortisol. Ucwaningo ngokugezwa kwamahlathi eJapan lukhombisa ukuthi imizuzu eyi-15 yokuchayeka kwemvelo inganciphisa amahomoni okucindezeleka ngo-16%.
(3). Ukusikisela: “Yiya epaki ngezimpelasonto ukuze ‘uthole ukungcola’ - ubuchopho bakho buzobonga lawo magciwane ongawaboni.
3. I-Cleanroom: inkundla yempi efihliwe yokuncintisana kwezwe
(1). Ukuqonda isimo samanje emikhakheni esezingeni eliphezulu njengokwenza ama-chip, i-biomedicine, nobuchwepheshe be-aerospace, amagumbi ahlanzekile awasezona nje “izindawo ezingenalo uthuli”, kodwa ingqalasizinda yamasu yokuncintisana kuzwelonke kwezobuchwepheshe. Ngokuphindaphindeka kobuchwepheshe, ukwakhiwa kwamagumbi ahlanzekile esimanje kubhekene nezidingo ezisezingeni eliphakeme ezingakaze zibonwe ngaphambili.
(2). Kusukela kuma-chips angu-7nm kuya emithini yokugoma ye-mRNA, yonke impumelelo yobuchwepheshe besimanje incike endaweni ehlanzeke nakakhulu. Eshumini leminyaka elizayo, ngokuthuthukiswa okuqhumayo kwama-semiconductors, i-biomedicine, nobuchwepheshe be-quantum, ukwakhiwa kwamagumbi ahlanzekile kuzothuthukiswa kusuka "kwizikhungo ezisizayo" kuya "kumathuluzi okukhiqiza ayisisekelo".
(3). Amakamelo okuhlanza ayinkundla yempi engabonakali yamandla obuchwepheshe bezwe emhlabeni omncane ongabonakali ngeso lenyama. Yonke inqubo yokwanda kwenhlanzeko ingavula imboni yezinga lezigidigidi.
Abantu abadingi nje kuphela izindawo zezimboni ezihlanzeke kakhulu, kodwa futhi abakwazi ukwenza ngaphandle “kobungqabavu besiphithiphithi” bemvelo. Laba bobabili babonakala bephikisana, kodwa empeleni, ngamunye udlala indima yakhe futhi asekela ngokubambisana impucuko yesimanje nempilo.
Isikhathi sokuthumela: Sep-17-2025